Search on: IMMUNOGLOBULIN LIGHT CHAINS, SURROGATE 
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Descriptor English:   Immunoglobulin Light Chains, Surrogate 
Descriptor Spanish:   Inmunoglobulina de Cadenas Ligeras Subrogadas 
Descriptor Portuguese:   Cadeias Leves Substitutas da Imunoglobulina 
Synonyms English:   Surrogate Immunoglobulin Light Chains
Surrogate Light Chains  
Tree Number:   D12.776.124.486.485.705.750.775
D12.776.124.486.485.950.750.500
D12.776.124.790.651.705.750.775
D12.776.124.790.651.950.750.500
D12.776.377.715.548.705.750.775
D12.776.377.715.548.950.750.500
D12.776.543.750.705.816.821.750.500
Definition English:   An immunolglobulin light chain-like protein composed of an IMMUNOGLOBULIN VARIABLE REGION-like peptide (such as light chain like lambda5 peptide) and an IMMUNOGLOBULIN CONSTANT REGION-like peptide (such as Vpreb1 peptide). Surrogate light chains associate with MU IMMUNOGLOBULIN HEAVY CHAINS in place of a conventional immunoglobulin light chains to form pre-B cell receptors. 
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
CT contraindications DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PD pharmacology PH physiology
PO poisoning RE radiation effects
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52787 
Unique Identifier:   D054444 

Occurrence in VHL:
 

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